Pub. Date : 2013 Dec
PMID : 24038465
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To understand the structural basis of this drug action, we previously determined the structure of human Top2 beta-isoform forming a cleavage complex with the drug etoposide and DNA, and described the insertion of drug into DNA cleavage site and drug-induced decoupling of catalytic groups. | Etoposide | DNA topoisomerase II beta | Homo sapiens |