Title : Development of a histone deacetylase 6 inhibitor and its biological effects.

Pub. Date : 2013 Sep 24

PMID : 24023063






1 Functional Relationships(s)
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1 Here, we show that a hydroxamic acid-based small-molecule N-hydroxy-4-(2-[(2-hydroxyethyl)(phenyl)amino]-2-oxoethyl)benzamide (HPOB) selectively inhibits HDAC6 catalytic activity in vivo and in vitro. Hydroxamic Acids histone deacetylase 6 Homo sapiens