Title : Acidosis drives damage-associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway.

Pub. Date : 2013 Oct 18

PMID : 24022484






2 Functional Relationships(s)
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1 Lactic acidosis, induced by the addition of 25 mm lactic acid, also induced the release of 20-kDa IL-1beta. Lactic Acid interleukin 1 beta Mus musculus
2 These data suggest that under disease relevant acidosis, DAMPs and lactic acid induce the secretion of IL-1beta independently of the inflammasome. Lactic Acid interleukin 1 beta Mus musculus