Title : Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane.

Pub. Date : 2013 Nov 15

PMID : 24013548






1 Functional Relationships(s)
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1 Exposure of MDCK cells maintained in low-Ca(2+) conditions to the CaSR agonists neomycin, Gd(3+) or R-568 causes the transient relocation of the tight junction components ZO-1 and occludin to sites of cell-cell contact, while inducing no significant changes in the expression of mRNAs encoding junction-associated proteins. Gadolinium tight junction protein 1 Canis lupus familiaris