Title : Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition.

Pub. Date : 2013 Nov 1

PMID : 24012377






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This elongated compound binds in an extended conformation to hCA II, with its tail lying towards the hydrophobic half of the active site whereas the sulfonamide moiety coordinates the zinc ion. Sulfonamides carbonic anhydrase 2 Homo sapiens