Title : Saucerneol F, a New Lignan Isolated from Saururus chinensis, Attenuates Degranulation via Phospholipase Cγ 1 Inhibition and Eicosanoid Generation by Suppressing MAP Kinases in Mast Cells.

Pub. Date : 2012 Nov

PMID : 24009845






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, we examined the effects of SF on the generation of 5-lipoxygenase (5-LO) dependent leukotriene C4 (LTC4), cyclooxygenase-2 (COX-2) dependent prostaglandin D2 (PGD2), and on phospholipase Cgamma1 (PLCgamma1)-mediated degranulation in SCF-induced mouse bone marrow-derived mast cells (BMMCs). Leukotriene C4 arachidonate 5-lipoxygenase Mus musculus