Title : Mitogen-activated protein kinase phosphatase-1 inhibition and sustained extracellular signal-regulated kinase 1/2 activation in camptothecin-induced human colon cancer cell death.

Pub. Date : 2013 Nov

PMID : 24005240






1 Functional Relationships(s)
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1 We found that HCT116 cells highly express mitogen-activated protein kinase phosphatase-1 (MKP1), which selectively inactivates extracellular signal-regulated kinase (ERK), whereas MKP1 levels were undetectable in CaCo2 cells. caco2 mitogen-activated protein kinase 1 Homo sapiens