Title : [Effect of curcumin combined with ATRA on differentiation of ATRA-resistant acute promyelocytic leukemia cells].

Pub. Date : 2013 Aug

PMID : 23998581






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1 ATRA could promote phosphorylation of AKT in NB4 cells at short time, but not had effect on phosphorylation of AKT in NB4-R1 cells; the curcumin could enhance the phosphorylation of AKT in NB4-1R cells, the curcumin combined with ATRA could further enhance the phosphorylation of AKT. Tretinoin AKT serine/threonine kinase 1 Homo sapiens