Title : Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.

Pub. Date : 2014 Mar 15

PMID : 23996800






1 Functional Relationships(s)
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1 Levels of N-acetyl-L-aspartate (NAA), the primary storage form of acetate in the brain, and aspartoacylase (ASPA), the enzyme responsible for NAA catalysis to generate acetate, are reduced in glioma; yet, few studies have investigated acetate as a potential therapeutic agent. N-acetylaspartate aspartoacylase Homo sapiens