Title : NLRP3 inflammasome activation in D-galactosamine and lipopolysaccharide-induced acute liver failure: role of heme oxygenase-1.

Pub. Date : 2013 Dec

PMID : 23994575






2 Functional Relationships(s)
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1 HO-1 induction with hemin reversed the lethality induced by GalN/LPS administration, and ZnPP pretreatment blocked this change. Galactosamine heme oxygenase 1 Mus musculus
2 Furthermore, HO-1 overexpression may protect the liver against GalN/LPS-induced inflammation through suppression of the NLRP3 signaling pathway. Galactosamine heme oxygenase 1 Mus musculus