Title : Crosstalk between the angiotensin and endothelin-system in the cerebrovasculature.

Pub. Date : 2013 Nov

PMID : 23988026






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Under losartan the ET-1 induced contraction is decreased. Losartan endothelin 1 Rattus norvegicus
2 In precontracted vessels under losartan and BQ-123, an ET(A)-receptor antagonist, ET-1 induced a higher relaxation. Losartan endothelin 1 Rattus norvegicus
3 Losartan has a dose-dependent antagonistic effect to the ET-1 induced contraction, which seems to ET(B)-receptor dependent. Losartan endothelin 1 Rattus norvegicus