Pub. Date : 2014 Jan
PMID : 23981688
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Modulation of Dcytb (Cybrd 1) expression and function by iron, dehydroascorbate and Hif-2alpha in cultured cells. | Dehydroascorbic Acid | cytochrome b reductase 1 | Homo sapiens |
2 | Modulation of Dcytb (Cybrd 1) expression and function by iron, dehydroascorbate and Hif-2alpha in cultured cells. | Dehydroascorbic Acid | cytochrome b reductase 1 | Homo sapiens |
3 | RESULTS: Iron and dehydroascorbic acid treatment of cells inhibited Dcytb mRNA and protein expression. | Dehydroascorbic Acid | cytochrome b reductase 1 | Homo sapiens |
4 | CONCLUSIONS: Taken together, this study shows the functional regulation of Dcytb reductase activity by DHA and Hif-2alpha. | Dehydroascorbic Acid | cytochrome b reductase 1 | Homo sapiens |
5 | GENERAL SIGNIFICANCE: Dcytb is a plasma membrane protein that accepts electrons intracellularly from DHA/ascorbic acid for ferrireduction at the apical surface of cultured cells and enterocytes. | Dehydroascorbic Acid | cytochrome b reductase 1 | Homo sapiens |