Title : Modulation of Dcytb (Cybrd 1) expression and function by iron, dehydroascorbate and Hif-2α in cultured cells.

Pub. Date : 2014 Jan

PMID : 23981688






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Modulation of Dcytb (Cybrd 1) expression and function by iron, dehydroascorbate and Hif-2alpha in cultured cells. Dehydroascorbic Acid cytochrome b reductase 1 Homo sapiens
2 Modulation of Dcytb (Cybrd 1) expression and function by iron, dehydroascorbate and Hif-2alpha in cultured cells. Dehydroascorbic Acid cytochrome b reductase 1 Homo sapiens
3 RESULTS: Iron and dehydroascorbic acid treatment of cells inhibited Dcytb mRNA and protein expression. Dehydroascorbic Acid cytochrome b reductase 1 Homo sapiens
4 CONCLUSIONS: Taken together, this study shows the functional regulation of Dcytb reductase activity by DHA and Hif-2alpha. Dehydroascorbic Acid cytochrome b reductase 1 Homo sapiens
5 GENERAL SIGNIFICANCE: Dcytb is a plasma membrane protein that accepts electrons intracellularly from DHA/ascorbic acid for ferrireduction at the apical surface of cultured cells and enterocytes. Dehydroascorbic Acid cytochrome b reductase 1 Homo sapiens