Pub. Date : 2002 Oct
PMID : 23978861
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The objective of the study was to investigate protective effects of ascorbic acid on lipid peroxidative damage and perturbation of enzymes, glucose-6-phosphate dehydrogenase (G6PDH) and acetylcholinesterase (AChE) in discrete regions of rat brain after vanadium exposure. | Vanadium | acetylcholinesterase | Rattus norvegicus |
2 | Interestingly, however, co-administration (L-ascorbic acid + vanadium) reversed the levels of ascorbic acid together with the activity of G6PDH and AChE towards normal values. | Vanadium | acetylcholinesterase | Rattus norvegicus |
3 | CONCLUSION: These results suggested that vanadium neurotoxicity initiated lipid peroxidative damage and interferes with enzymes, G6PDH and AChE, in rat brain. | Vanadium | acetylcholinesterase | Rattus norvegicus |