Title : Substitution p.A350V in Na⁺/Mg²⁺ exchanger SLC41A1, potentially associated with Parkinson's disease, is a gain-of-function mutation.

Pub. Date : 2013

PMID : 23976986






1 Functional Relationships(s)
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1 Interestingly, gene SLC41A1 located in the novel PD locus PARK16 has recently been identified as being a Na+/Mg2+ exchanger (NME, Mg2+ efflux system), a key component of cellular magnesium homeostasis. Magnesium solute carrier family 41 member 1 Homo sapiens