Title : The effect of pyridostigmine and physostigmine on acute toxicity of diisopropyl fluorophosphate in rats.

Pub. Date : 1990 Mar

PMID : 2396896






2 Functional Relationships(s)
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1 Diisopropyl fluorophosphate (DFP) given to rats in lethal concentration (100 mg/m3, by inhalation for 40 min) significantly inhibited acetylcholinesterase activity in the blood, lung, liver and brain, and induced hyperglycaemia and glycogen mobilization in the liver, diaphragm and brain. Isoflurophate acetylcholinesterase Rattus norvegicus
2 Diisopropyl fluorophosphate (DFP) given to rats in lethal concentration (100 mg/m3, by inhalation for 40 min) significantly inhibited acetylcholinesterase activity in the blood, lung, liver and brain, and induced hyperglycaemia and glycogen mobilization in the liver, diaphragm and brain. Isoflurophate acetylcholinesterase Rattus norvegicus