Title : Pretreatment with sildenafil alleviates early lung ischemia-reperfusion injury in a rat model.

Pub. Date : 2013 Dec

PMID : 23953793






1 Functional Relationships(s)
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1 Compared with the saline + I/R group, sildenafil + I/R group had significant decreases in Bax, p53, Bax/Bcl-2 ratio, caspase 3, IL-6, TNF-alpha level, and W/D weight ratio but an increase in Bcl-2 expression (P < 0.05). Sildenafil Citrate caspase 3 Rattus norvegicus