Title : Statins in lymphangioleiomyomatosis. Simvastatin and atorvastatin induce differential effects on tuberous sclerosis complex 2-null cell growth and signaling.

Pub. Date : 2013 Nov

PMID : 23947572






1 Functional Relationships(s)
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1 Simvastatin, but not atorvastatin, inhibited the activity of prosurvival serine-threonine kinase Akt and induced marked up-regulation of cleaved caspase-3, a marker of cell apoptosis. Simvastatin AKT serine/threonine kinase 1 Homo sapiens