Title : Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38.

Pub. Date : 2013 Nov

PMID : 23938254






1 Functional Relationships(s)
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1 Furthermore, they inhibited the expression of the allergic cytokines, IL-4 and TNF-alpha as well as the activation of their transcription factors NF-kappaB, AP-1 and p38 in histamine-stimulated skin tissues. Histamine interleukin 4 Mus musculus