Pub. Date : 2013 Nov 28
PMID : 23933235
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Despite the clinical introduction of an increasing number of polyethylene glycol (PEG)-conjugated substances, PEG has been named as the cause of an unexpected immunogenic response known as the "accelerated blood clearance (ABC) phenomenon." | Polyethylene Glycols | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
| 2 | Despite the clinical introduction of an increasing number of polyethylene glycol (PEG)-conjugated substances, PEG has been named as the cause of an unexpected immunogenic response known as the "accelerated blood clearance (ABC) phenomenon." | Polyethylene Glycols | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
| 3 | In addition, the clinical implications of the ABC phenomenon on the therapeutic efficacy of PEG-conjugated substances/PEGylated nanocarriers, along with the new approaches that can be applied to manage and/or abrogate the induction of the ABC phenomenon, are also discussed. | Polyethylene Glycols | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |
| 4 | In addition, the clinical implications of the ABC phenomenon on the therapeutic efficacy of PEG-conjugated substances/PEGylated nanocarriers, along with the new approaches that can be applied to manage and/or abrogate the induction of the ABC phenomenon, are also discussed. | Polyethylene Glycols | ATP binding cassette subfamily B member 6 (Langereis blood group) | Homo sapiens |