Title : Pharmacogenetics of olanzapine metabolism.

Pub. Date : 2013 Aug

PMID : 23930678






2 Functional Relationships(s)
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1 The formation of the various olanzapine metabolites is influenced by polymorphisms in the genes coding for CYP1A2, CYP1A expression regulator AHR, UGT1A4 and UGT2B10, as well as FMO3. Olanzapine cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 An impact on steady-state olanzapine serum concentrations has been suggested for variants of CYP1A2 and UGT1A4, with somewhat conflicting findings. Olanzapine cytochrome P450 family 1 subfamily A member 2 Homo sapiens