Pub. Date : 2013 Sep
PMID : 23925977
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Renin-angiotensin systems are known to act in many tissues, for example, the blood vessel wall or kidney, where a close interaction between angiotensin and dopamine has been demonstrated. | Dopamine | renin | Homo sapiens |
2 | In animal models, dopamine depletion induces compensatory overactivation of the local renin-angiotensin system, which primes microglial responses and neuron vulnerability by activating NADPH-oxidase. | Dopamine | renin | Homo sapiens |
3 | In this review we provide evidence suggesting that the renin-angiotensin system may play an important role in dopamine"s mediated neuroinflammation and oxidative stress changes in Parkinson"s disease. | Dopamine | renin | Homo sapiens |