Title : Tetrandrine potentiates the hypoglycemic efficacy of berberine by inhibiting P-glycoprotein function.

Pub. Date : 2013

PMID : 23924821






2 Functional Relationships(s)
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1 In the in vitro experiments, Tet significantly inhibited the efflux and increased the uptake of P-gp substrates rhodamine-123 as well as BBR in MCF7/DOX cells and Caco-2 intestinal cells. tetrandrine phosphoglycolate phosphatase Homo sapiens
2 Meanwhile, Tet greatly reduced the expression of P-gp in Caco-2 cells. tetrandrine phosphoglycolate phosphatase Homo sapiens