Title : Ribonucleotide reductase large subunit M1 predicts poor survival due to modulation of proliferative and invasive ability of gastric cancer.

Pub. Date : 2013

PMID : 23922955






1 Functional Relationships(s)
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1 Furthermore, inhibition of RRM1 by siRNA significantly reduced the dNTP pool, Ras/Raf and MMP-9 activities and the levels of p-MEK, p-ERK and NF-kappaB, resulting in growth retardation and reduced invasion in AGS and NCI-N87 cells. Parathion ribonucleotide reductase catalytic subunit M1 Homo sapiens