Title : Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction.

Pub. Date : 2013 Nov 1

PMID : 23909401






2 Functional Relationships(s)
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1 Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction. Phosphatidylinositol 4,5-Diphosphate proline rich transmembrane protein 2 Homo sapiens
2 Our studies show that collaboration between AMPK and PKC dictates the extent of Ser413 phosphorylation on PIP5K1B and regulates PtdIns(4,5)P2 synthesis. Phosphatidylinositol 4,5-Diphosphate proline rich transmembrane protein 2 Homo sapiens