Pub. Date : 2013 Oct 1
PMID : 23906928
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Chronomodulated radiosensitization of TPT was investigated by analysis of tumor regrowth delay (TGD), pimonidazole hydrochloride, histone H2AX phosphorylation, (gamma-H2AX) topoisomerase I (Top I), cell cycle, and apoptosis after treatment with (1) TPT (10 mg/kg) alone; (2) radiation therapy alone (RT); and (3) TPT+RT at 3, 9, 15, and 21 HALO. | Topotecan | DNA topoisomerase I | Homo sapiens |
2 | Chronomodulated radiosensitization of TPT was investigated by analysis of tumor regrowth delay (TGD), pimonidazole hydrochloride, histone H2AX phosphorylation, (gamma-H2AX) topoisomerase I (Top I), cell cycle, and apoptosis after treatment with (1) TPT (10 mg/kg) alone; (2) radiation therapy alone (RT); and (3) TPT+RT at 3, 9, 15, and 21 HALO. | Topotecan | DNA topoisomerase I | Homo sapiens |
3 | The expression of Top I in the TPT+RT group was also significantly different from the control tumors at 15 HALO (P<.05). | Topotecan | DNA topoisomerase I | Homo sapiens |