Title : Inhibition of Drp1-dependent mitochondrial division impairs myogenic differentiation.

Pub. Date : 2013 Oct 15

PMID : 23904108






2 Functional Relationships(s)
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1 We found that differentiation of C2C12 myoblasts induced by serum starvation was accompanied by a gradual increase in Drp1 protein expression (to ~350% up to 3 days) and a fast reduction of Drp1 phosphorylation at Ser-637 (to ~30%) resulting in translocation of Drp1 protein from the cytosol to mitochondria. Serine dynamin 1-like Mus musculus
2 We found that differentiation of C2C12 myoblasts induced by serum starvation was accompanied by a gradual increase in Drp1 protein expression (to ~350% up to 3 days) and a fast reduction of Drp1 phosphorylation at Ser-637 (to ~30%) resulting in translocation of Drp1 protein from the cytosol to mitochondria. Serine dynamin 1-like Mus musculus