Pub. Date : 1990 Jul
PMID : 2390138
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Influence of apo E polymorphism on the response to simvastatin treatment in patients with heterozygous familial hypercholesterolemia. | Simvastatin | low density lipoprotein receptor | Homo sapiens |
| 2 | In the combined FH patient group (males and females) a considerable interindividual variation in response to simvastatin was observed, but was not related to the apoE polymorphism. | Simvastatin | low density lipoprotein receptor | Homo sapiens |
| 3 | However, considering males and females separately, we found that female FH patients with the apoE3E3 phenotype responded better on simvastatin treatment with respect to LDL-cholesterol than male FH patients with the apoE3E3 phenotype. | Simvastatin | low density lipoprotein receptor | Homo sapiens |