Title : Sub-chronic exposure to the insecticide dimethoate induces a proinflammatory status and enhances the neuroinflammatory response to bacterial lypopolysaccharide in the hippocampus and striatum of male mice.

Pub. Date : 2013 Oct 15

PMID : 23891859






2 Functional Relationships(s)
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1 Dimethoate increased mRNA levels of tumor necrosis factor alpha (TNFalpha) and interleukin (IL) 6 in the hippocampus, and increased the proportion of Iba1 immunoreactive cells with reactive phenotype in dentate gyrus and striatum. Dimethoate interleukin 6 Mus musculus
2 Some of the effects of lipopolysaccharide (proportion of Iba1 immunoreactive cells with reactive phenotype and IL6 mRNA levels) were amplified in the animals treated with dimethoate, but only in the striatum. Dimethoate interleukin 6 Mus musculus