Title : Pin1 promotes GR transactivation by enhancing recruitment to target genes.

Pub. Date : 2013 Oct

PMID : 23887939






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Unrestricted proline isomerisation can be inhibited by adjacent serine phosphorylation and requires a prolyl isomerise, Pin1. Proline peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens
2 Pin1 therefore determines the functional outcome of proline-directed kinases acting on the GR, as cis/trans isomers are distinct pools with different interacting proteins. Proline peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Homo sapiens