Title : Differential regulation of human 3β-hydroxysteroid dehydrogenase type 2 for steroid hormone biosynthesis by starvation and cyclic AMP stimulation: studies in the human adrenal NCI-H295R cell model.

Pub. Date : 2013

PMID : 23874725






1 Functional Relationships(s)
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Protein Name
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1 Type 2 HSD3B catalyzes the conversion of pregnenolone, 17alpha-hydroxypregnenolone and dehydroepiandrosterone to progesterone, 17alpha-hydroxyprogesterone and androstenedione in the human adrenal cortex and the gonads but the exact regulation of this enzyme is unknown. Progesterone hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Homo sapiens