Title : The carbonylation and covalent dimerization of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity is inhibited by the radical scavenger tempol.

Pub. Date : 2013 Oct 1

PMID : 23855710






4 Functional Relationships(s)
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Protein Name
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1 The carbonylation and covalent dimerization of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity is inhibited by the radical scavenger tempol. tempol superoxide dismutase 1 Homo sapiens
2 As a result, tempol was consumed nearly stoichiometrically with hSOD1 monomers. tempol superoxide dismutase 1 Homo sapiens
3 Tempol consumption by the bicarbonate-dependent peroxidase activity of hSOD1 may be one of the reasons why high doses of tempol were required to afford protection in an ALS rat model. tempol superoxide dismutase 1 Homo sapiens
4 Tempol consumption by the bicarbonate-dependent peroxidase activity of hSOD1 may be one of the reasons why high doses of tempol were required to afford protection in an ALS rat model. tempol superoxide dismutase 1 Homo sapiens