Title : Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis.

Pub. Date : 2013 Sep

PMID : 23852422






2 Functional Relationships(s)
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Protein Name
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1 Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis. Hydrogen Peroxide tumor protein p53 Homo sapiens
2 Finally, increased hydrogen peroxide was found to mediate Chk1 phosphorylation at Ser345, p53 protein induction, cell apoptotic induction, and transformation inhibition following Chel A treatment. Hydrogen Peroxide tumor protein p53 Homo sapiens