Title : AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons.

Pub. Date : 2013 Oct

PMID : 23841933






1 Functional Relationships(s)
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Protein Name
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1 Activation of AMPK, which is induced by glucose deprivation, treatment with pharmacological agents such as 2-deoxy-D-glucose, metformin, and 5-aminoimidazole-4-carboxamide ribonucleoside or forced expression of a constitutively active AMPKalpha subunit, counteracts BDNF-induced phosphorylation of p70S6K and enhanced protein synthesis in cortical neurons. acadesine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens