Title : [Tetrandrine reversed the resistance of tamoxifen in human breast cancer MCF-7/TAM cells: an experimental research].

Pub. Date : 2013 Apr

PMID : 23841269






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The effects of multidrug resistance protein 1 (MRP1) gene of Tet on MCF-7iTAM cells were detected by real-time fluorescence quantitative PCR. tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
2 The effects of multidrug resistance protein 1 (MRP1) gene of Tet on MCF-7iTAM cells were detected by real-time fluorescence quantitative PCR. tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
3 MRP1 was reduced at gene (P <0.05) and protein levels when Tet effected on MCF-7ITAM cells. tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens
4 CONCLUSION: Tet could reverse the drug resistance of MCF-7/TAM cells, and the reverse mechanism may be related to down-regulating MRP1 expression. tetrandrine ATP binding cassette subfamily B member 1 Homo sapiens