Pub. Date : 2013
PMID : 23840832
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Palmitic acid induces osteoblastic differentiation in vascular smooth muscle cells through ACSL3 and NF-kappaB, novel targets of eicosapentaenoic acid. | Palmitic Acid | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Notably, PA induced activation of NF-kappaB, and NF-kappaB inhibitor prevented PA-induction of osteoblastic gene expression and calcium deposition. | Palmitic Acid | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | Notably, PA induced activation of NF-kappaB, and NF-kappaB inhibitor prevented PA-induction of osteoblastic gene expression and calcium deposition. | Palmitic Acid | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | Notably, PA induced activation of NF-kappaB, and NF-kappaB inhibitor prevented PA-induction of osteoblastic gene expression and calcium deposition. | Palmitic Acid | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | These results identify ACSL3 and NF-kappaB as mediators of PA-induced osteoblastic differentiation and calcium deposition in VSMC and suggest that EPA prevents vascular calcification by inhibiting such a new molecular pathway elicited by PA. | Palmitic Acid | nuclear factor kappa B subunit 1 | Homo sapiens |