Title : Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domain.

Pub. Date : 2013 Nov

PMID : 23838006






1 Functional Relationships(s)
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1 Aldosterone stimulated phosphorylation of MAP kinases and increased expression of pro-inflammatory mediators ICAM-1, Cox-2 and PAI-1 in Deltakinase and K1648R cells, effects that were inhibited by eplerenone (mineralocorticoid receptor (MR) blocker). Eplerenone mitochondrially encoded cytochrome c oxidase II Homo sapiens