Title : Synthesis and anti-HIV-1 screening of novel N'-(1-(aryl)ethylidene)-2-(5,5-dioxido-3-phenylbenzo[e]pyrazolo[4,3-c][1,2]thiazin-4(1H)-yl)acetohydrazides.

Pub. Date : 2014 Nov

PMID : 23835833






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compound 5i exhibited the most potent anti-HIV-1 activity (EC50 = 3.2 muM) while 5h showed anti-HIV-1 activity (EC50 = 3.8 muM) with no toxicity at all in primary human lymphocytes, CEM and VERO cells. 5h latexin Homo sapiens