Title : Development and characterization of a non-cell-based assay to assess the presence of neutralizing antibodies to interferon-beta in clinical samples.

Pub. Date : 2013 Sep 30

PMID : 23831137






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This NAb assay utilizes an electrochemiluminescence detection platform and is based on the first step involved in all IFN-beta-induced biological activities, namely the binding of IFN-beta to its receptor, which is inhibited when NAbs are present. nab interferon beta 1 Homo sapiens
2 This NAb assay utilizes an electrochemiluminescence detection platform and is based on the first step involved in all IFN-beta-induced biological activities, namely the binding of IFN-beta to its receptor, which is inhibited when NAbs are present. nab interferon beta 1 Homo sapiens
3 Using this approach, NAb titers in clinical samples from multiple sclerosis patients treated with IFN-beta were determined and compared with those obtained using existing cell-based NAb assays. nab interferon beta 1 Homo sapiens