Title : Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.

Pub. Date : 2013 Nov 15

PMID : 23825108






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In cblG, mutations in methionine synthase (MTR) decrease conversion of hydroxocobalamin (HOCbl) to methylcobalamin, while in cblC, mutations in MMACHC disrupt formation of cob(II)alamin (detected as HOCbl). Hydroxocobalamin 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens
2 In cblG, mutations in methionine synthase (MTR) decrease conversion of hydroxocobalamin (HOCbl) to methylcobalamin, while in cblC, mutations in MMACHC disrupt formation of cob(II)alamin (detected as HOCbl). Hydroxocobalamin 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens
3 In cblG, mutations in methionine synthase (MTR) decrease conversion of hydroxocobalamin (HOCbl) to methylcobalamin, while in cblC, mutations in MMACHC disrupt formation of cob(II)alamin (detected as HOCbl). Hydroxocobalamin 5-methyltetrahydrofolate-homocysteine methyltransferase Homo sapiens