Title : Factors Affecting Aggregate Formation in Cell Models of Huntington's Disease and Amyotrophic Lateral Sclerosis.

Pub. Date : 2013 Apr

PMID : 23819039






1 Functional Relationships(s)
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1 The siRNA technology was used to show that the inhibition of GAPDH expression leads to a 45-50% reduction in the aggregation of mutant huntingtin, with a repeat of 103 glutamine residues in a model of Huntington"s disease (HD). Glutamine huntingtin Homo sapiens