Title : Angiotensin-converting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways.

Pub. Date : 2013 Aug 10

PMID : 23816468






1 Functional Relationships(s)
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Protein Name
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1 Exposure to Ang II resulted in significant increases in suppressor of cytokine signaling 3 (SOCS3) expression and phosphorylation levels of JAK2, STAT3 and ERK1/2 linked with elevated superoxide production and cell proliferation in HUASMCs. Superoxides mitogen-activated protein kinase 3 Homo sapiens