Title : PPARĪ“ induces estrogen receptor-positive mammary neoplasia through an inflammatory and metabolic phenotype linked to mTOR activation.

Pub. Date : 2013 Jul 15

PMID : 23811944






1 Functional Relationships(s)
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1 The appearance of malignant changes correlated with a pronounced increase in phosphatidylcholine and lysophosphatidic acid metabolites, which coincided with activation of Akt and mTOR signaling that were attenuated by treatment with the mTOR inhibitor everolimus. Phosphatidylcholines thymoma viral proto-oncogene 1 Mus musculus