Title : Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism.

Pub. Date : 2013

PMID : 23805127






1 Functional Relationships(s)
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1 Inhibition assays using human liver microsomes (HLM) incubated with 19-norandrosterone and selective inhibitors confirmed that UGT2B7 and UGT2B15 are involved in 19-norandrosterone glucuronidation, since the presence of the specific UGT2B7 and UGT2B15 inhibitors gemfibrozil and valproic acid inhibited the 19-norandrosterone glucuronidation by 35 and 45%, respectively. Valproic Acid UDP glucuronosyltransferase family 2 member B15 Homo sapiens