Title : How metabolism generates signals during innate immunity and inflammation.

Pub. Date : 2013 Aug 9

PMID : 23798679






1 Functional Relationships(s)
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1 In addition, the extracellular overproduction of metabolites such as uric acid and cholesterol crystals acts as a signal sensed by NLRP3, leading to the production of IL-1beta. Cholesterol NLR family pyrin domain containing 3 Homo sapiens