Title : Olmesartan decreases IL-1β and TNF-α levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis.

Pub. Date : 2013 Oct

PMID : 23775504






2 Functional Relationships(s)
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1 Olmesartan decreases IL-1beta and TNF-alpha levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis. olmesartan interleukin 1 beta Rattus norvegicus
2 In addition, the group that was treated with 6 mg/kg olmesartan showed a decreased level of IL-1beta (p < 0.05), and all doses of olmesartan resulted in decreased levels of TNF-alpha. olmesartan interleukin 1 beta Rattus norvegicus