Pub. Date : 2013 Oct
PMID : 23775504
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Olmesartan decreases IL-1beta and TNF-alpha levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis. | olmesartan | interleukin 1 beta | Rattus norvegicus |
2 | In addition, the group that was treated with 6 mg/kg olmesartan showed a decreased level of IL-1beta (p < 0.05), and all doses of olmesartan resulted in decreased levels of TNF-alpha. | olmesartan | interleukin 1 beta | Rattus norvegicus |