Title : 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.

Pub. Date : 2013 Jul 4

PMID : 23760478






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Lysine BP1 Homo sapiens
2 53BP1 binds to nucleosomes minimally as a dimer using its previously characterized methyl-lysine-binding Tudor domain and a carboxy-terminal extension, termed the ubiquitination-dependent recruitment (UDR) motif, which interacts with the epitope formed by H2AK15ub and its surrounding residues on the H2A tail. Lysine BP1 Homo sapiens