Pub. Date : 2013 May
PMID : 23760395
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Moreover, we observed that MQ-mediated ROS simultaneously downregulated Akt phosphorylation and activated extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and adenosine monophosphate-activated protein kinase (AMPK) signaling in PC3 cells. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | Moreover, we observed that MQ-mediated ROS simultaneously downregulated Akt phosphorylation and activated extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and adenosine monophosphate-activated protein kinase (AMPK) signaling in PC3 cells. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |