Title : Enhanced antitumor activity of cerulenin combined with oxaliplatin in human colon cancer cells.

Pub. Date : 2013 Aug

PMID : 23754252






3 Functional Relationships(s)
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1 In combination with cerulenin and oxaliplatin, activation of the p53-p21 pathway and p38 occurred in a smaller concentration and finally induced caspase-3 cleavage in a smaller concentration of cerulenin and oxaliplatin. Oxaliplatin tumor protein p53 Homo sapiens
2 Oxaliplatin induced activation of the p53-p21 pathway and p38. Oxaliplatin tumor protein p53 Homo sapiens
3 In combination with cerulenin and oxaliplatin, activation of the p53-p21 pathway and p38 occurred in a smaller concentration and finally induced caspase-3 cleavage in a smaller concentration of cerulenin and oxaliplatin. Oxaliplatin tumor protein p53 Homo sapiens