Pub. Date : 2013 Oct
PMID : 23752093
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | mTORC1-dependent protein synthesis underlying rapid antidepressant effect requires GABABR signaling. | gababr | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | In vivo, blocking GABABR prevents the fast-acting, anti-depressant effect of the NR2B antagonist, Ro-25-6891, decreases active mTORC1 kinase, and reduces expression of BDNF and the AMPA receptor subunit GluA1. | gababr | CREB regulated transcription coactivator 1 | Mus musculus |