Title : ROS are required for mouse spermatogonial stem cell self-renewal.

Pub. Date : 2013 Jun 6

PMID : 23746981






1 Functional Relationships(s)
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1 SSCs depleted of ROS stopped proliferating, but they showed enhanced self-renewal when ROS levels were increased by the addition of hydrogen peroxide, which induced the phosphorylation of stress kinases p38 mitogen-activated protein kinase (MAPK) and c-jun N-terminal kinase (JNK). Hydrogen Peroxide mitogen-activated protein kinase 14 Mus musculus